目前癌症使用化療放療藥物非禁忌症,只是疫苗效果較差。
目前癌症使用化療放療藥物非禁忌症,只是疫苗效果較差。
化放療導致血小板低下:大於2萬就能打, 請注意止血
5-FU、oxaliplatin、Irinotecan、Stivagra、Glivec、Sutent
避免同一天打:
Cytotoxic chemotherapy, Monoclonal Antibodies (with cytotoxic chemotherapy), Immunotherapy (IO) (with cytotoxic chemotherapy), Proteosome Inhibitors (e.g. bortezomib, ixazomib)
不改變施打時程:Monoclonal Antibodies (single agent), Immunotherapy (IO) (single agent), Small molecule protein kinase inhibitors (TKIs), Immunomodulatory (IMiDs)
Radiotherapy, R/T, RT, RTx, radiation therapy, 放療, 放射線治療, 電療:不改變施打時程
Chemo-Radiotherapy:最好打疫苗後再去做
Intravenous chemotherapy e.g. carboplatin, cisplatin, mitomycin:避免同天
Continuous capecitabine, temozolamide:不改變施打時程
Talimogene laherparepvec (T-VEC) :第一劑避免同天, 第二劑沒差
不改變施打時程:Hormone treatments and other supportive treatments, Bladder instillations (BCG, mitomycin, gemcitabine, epirubicin etc) (small chance of systemic absorption)
不改變施打時程:PARP inhibitors (e.g. olaparib, rucaparib), CDK4/6 inhibitors (e.g. abemaciclib, ribociclib, palbociclib)
neutropenia, leukopenia, 白血球滴低下:ANC > 1000(不是打GCSF之類打出來的)加上無不適可以打
對化療藥物過敏的可能要注意某些疫苗可能含同樣的賦型劑
Taxanes過敏:選AZ